Pharmaceutical Applications
Tulsion® resins find a number of applications as Excipients in pharmaceutical formulations.

APPLICATIONS: The use in pharmaceutical formulations can be classified under one of the following four categories:

  • Drug stabilization- Drugs for instance, Vitamin B-12 when stored, degenerate after some time. The stabilization of such drugs can be brought about using Tulsion® resins

  • Sustained release- Sustained release formulations ensure that the drug is released continuously into the body at a slower, but steady rate. The release of drugs from ion exchange resins depends upon a aeries of ionic reactions between various body fluids and the drug-resin complex. The rate of release of drug can be controlled by varying the particle size, degree of cross-linking and the chemistry of resin. The release profile can almost be tailor made to suit a particular application.

  • Taste masking agent- Certain drugs that have a very bitter taste can be made relatively tasteless by absorbing the drugs on Tulsion® exchange resins. The pH in the mouth being on the basic side compared to the pH in the stomach, the complex drug will not release in the mouth but only in the stomach. Since while passing through the mouth the drug remains in complex form, no or very little taste is imparted.
    The resins are used in fine mesh form. The nature of the resin used is also dependant upon the type of drug being masked.

  • Tablet disintegrant- In order to ensure that once a tablet is ingested, the desired drug is delivered, it is desirable that the tablet disintegrates uniformly and quickly. External agents are added to a tablet formulation to ensure the disintegration. Tuslion reins can be used as a disintegrating agent. This is due to the fact that the resin will swell significantly once it imbibes moisture. Since the resin in Potassium form swells much more than the resin in Hydrogen firm, Potassium form of the resin is preferred in this application.
       Tulsion®
FEATURES
     T- 44: Cation exchange resin manufactured to high standard pharmaceutical quality. Used for sustained release.
     T-335: Supplied in powder form having no side reaction and having good taste masking ability. Used for taste masking ability. Used for taste masking, Vitamin B12 recovery and stabilization
     T-339: Supplied in powder form having no side reaction and having good taste masking ability. Used for taste masking ability. Used for taste masking & tablet disintegration
     T-343: Light brown coloured free flowing powder. Used for sustained release and taste masking
     T-344: Light coloured free flowing powder. Used for sustained release and taste masking
     CXO-17: Fine particle size resin. Specially purified to high standard pharmaceutical quality acrylic resin for chromatographic separation. Used for purification of antibiotics.
     CXO-18: Premium grade highly purified acrylic resin. Used for purification of antibiotics.

 

Packaging (Dry form)
             HDPE Carbuoys   25 kgs   55 lbs
Packaging (Wet form)
                            Fibre drums   7 cft
                            MS drums   180 cft


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